Neotame is an artificial sweetener with off-white to white powder and an intensely sweet taste. Neotame is manufactured from 3,3 –dimethylbutyraldehyde and aspartame. Neotame purification and isolation is carried out by distillation of a portion of the methanol followed by addition of water. Neotame comes in the second generation of artificial sweetener followed by sucralose. Neotame …