Discovering Possibilities to Treat Huntington’s Disease

Medical science has been successful in various aspects in terms of treating diseases that had no cure earlier. Similar dilemma was being experienced with the process of finding a possible treatment for neurodegenerative diseases. Even after achieving advancement in the various genetic diseases, researchers have repeatedly failed to taste success in case of Huntington’s disease. This genetic neurological disease, having no definite cure, is an inherited disorder that kills brain cells. Progressing towards death, this rare disease is diagnosed in the 30s-40s of age. The disease deteriorates patients’ physical and mental abilities. Weight-loss is one prominent complication that worsens the symptoms and weakens the patients.

Researchers have been seeking the probable treatments or therapies which could help control the progressing symptoms, if not entirely cure this fatal disorder. Current medications are observed only to help control one of its symptoms of involuntary movements, however, provide no great help in suppressing the disease.

Study conducted to achieve the control on Huntington’s disease

Duke University’s neurologist, Dr. La Spada’s team focused on advancing in Huntington’s treatment for which they tested a drug developed for the treatment of diabetes. However, it was repurposed due to its ability to cross the blood-brain barrier. Similarly, they tested a cancer drug that enabled a mice having Huntington’s disease- like ailment, to move more easily and recover from brain deterioration. Several other tests and researches are being done in this context to combine the drugs for a better result.

A new theory that may potentially address Huntington’s disease

Canadian researchers are working on improving the situation of treatments and therapies. The research is based on the idea that talks about is rare type of signals received from damaged DNA indicating huntingtin activity in DNA repair. This signaling is flawed in Huntington’s disease which could result in shifting the course of the Huntington’s disease.

Cognitive advancement in Huntington’s disease patients due to D-PUFA

Using D-PUFA drug, there was a visible disease-modifying effect like cognition and movements on this rare neurodegenerative disease. D-PUFA was seen eliminating the usual obstacle in neurodegenerative diseases of not being able to access tissues.

Innovative research initiatives like these have the capabilities to break through the unsolved mysteries of this fatal ailment. The more the neurodegenerative diseases are studied, that closer, researchers would get to alter the course of Huntington’s disease

The Most Efficient and Convincing Small Business Tools

It is not always easy to find the right business tools to help automate your processes. Automation tools are like having an extra employee for a low monthly cost that will keep your business on track and ahead of your competition. However, before using any, it is always imperative to make sure if these business tools are right for your business – demos and free trials are always there.

Some of the most popular small business tools are listed below.

Trello: Some people use Trello for grocery lists, while others use it for their high-growth businesses. Different tasks can be easily moved around and tagged with other users. Or if you want to quickly check in or change something up, then Trello is one of the best business tools to have.

WorkflowMax: We are aware of the term that project management is a mess of paperwork, folders files, whiteboards, and calendars. WorkflowMax is one of the most efficient business tools that allows users to create professional, instant quotes for potential clients. This tool is perfect for freelancers and small businesses who needs to provide a service and bill based on time.

Slack: Slack is one of the most popular and amazing business tools that helps you to stay in touch with your team, by giving your team members a workspace with organized and accessible conversations. In Slack, a searchable archive of team conversations is available so that every team member has an access to the required answers.

Groove: Groove is one such business tools where you can quickly and easily set up all the customer service options you want in one place. The main focus of this business tools is helping the small businesses to grow and making easy for teams to work out of internally. This is an excellent option in all the business tools to keep your customer service simple and effective.

Asana: While talking about project management business tools, there is no other tool is even closer to Asana. Asana is fast, intuitive, and easy to manipulate. The arrangement features and user interface of Asana, makes it easy to navigate, prioritize, and organize. Asana also takes the form of a check list and you can mark tasks completed as you go. While working on projects, Asana makes it easy to communicate with your team members, since there are notes and comment sections for each project.

MailChimp: We all hate getting mails, but if we think as a marketer we all know that people still read the emails, and even if they don’t they at least see who is sending them emails. So getting into your potential, current, or past customers’ inbox is a joyous thing that you should take seriously. MailChimp is one such business tools that allows you to create automated email campaigns, so you need to do the work once, and let them do the rest for you.

Looking forward to Improved Business Responses to Customers? Chatbots is the Answer!

Chatbots are one of the most talked about technological wonders that has the potential to change the way businesses respond to customer queries. This extraordinary software is programmed to interact with humans in order to cater to their needs and queries. We have seen the application of chatbots in messaging apps to improve the users messaging experience. This technology is now transforming the processes of business entities.

When we talk about businesses adopting chatbots, there are various reasons why chatbots work just fine. Combining the aspects of messaging, human conversations and operability, chatbots help businesses to create a well-designed experience for their customers, resulting in faster and more efficient responses.

African businesses unleashing the power of technology with chatbots

Oracle recently announced the availability of mobile and chatbots capabilities in their Oracle Cloud Platform Services that would help businesses to adapt to the rapidly changing technological trends. In the mobile-centric age, it is essential for businesses to find better ways to engage with customers smartly. Customers today, expect personalized attention to their needs and support queries. Businesses are therefore, constantly indulging in active engagement and fast response techniques for their customers to provide them a better and cognitive experience. Hence, Oracle is here for their rescue, providing integrated, secure, well programmed and seamless services which include chatbots.

While there was a considerable rise of chatbots on messaging apps, they would now be incorporated in the banking sectors, e-commerce business as well as retail, a recent trend says. Creating a better user experience shows its implementation of advanced business strategy which could be very beneficial for businesses today. E-commerce businesses could successfully cater to their customer needs by being able to provide a good interactive support for all their customers worldwide. Chatbots don’t just improve the customer experience, but also help businesses become more cost effective and reduce the amount of human hours and revenue that goes into customer service.

Chatbots change the way businesses interact with their customers

Besides, chatbots have an access of broader array of information and can respond to service queries with greater accuracy and speed 24/7, so that the customers do not have to wait. They replace the humans for certain tasks related to customer assistance, leaving the human staff to take care of complex business processes. The increasing importance of customer satisfaction and better service for prospects along with advent of technologies businesses must adopt these newer and advanced technological innovations. With the changing requirements, the type of chatbots also keep changing so that businesses could to be adapting to the change

Advances in Sonodynamic Therapy (SDT) Offer a Promising Non-invasive Approach in Cancer Treatment

We are all well known of the fact that cancer has become the first killer of human health, and anticancer therapy has attracted more attention of researchers from all over the world. Currently, four main methods are clinically applied in cancer treatments but every kind of treatment has its own limitations which are the major challenges for cancer treatment.

Being developed as a novel promising noninvasive approach, Sonodynamic Therapy (SDT) is derived from photodynamic therapy (PDT). The major difference between Sonodynamic Therapy and Photodynamic Therapy is the energy source used to activate the sensitizers. Photodynamic therapy is not effective for the treatment of deep-seated tumors due to its short penetration depth of light. However, the significant advantage of Sonodynamic Therapy over Photodynamic Therapy is that ultrasound can be tightly focused with penetration in soft tissue up to several tens of centimeters.

Anticancer effect of Sonodynamic Therapy

With an evolving methodology, sonodynamic therapy offers the possibility of non-invasively eradicating solid tumors in a site-directed manner. A high therapeutic efficacy of sonodynamic therapy in cancers is resulting from the comprehensive functions. According to several investigations, it is confirmed that the production of a large amount of intracellular Reactive Oxygen Species (ROS) induced by sonodynamic therapy can produce direct cytotoxicity in cancer cells. The sonodynamic therapy can also possess the modulation effects on cancer microenvironment, e.g., the suppression effect on tumor vasculature and the stimulation effect on the tumor immunity, which inhibit the growth of cancers.

Role of sonosensitizers

Sonosensitizer is considered as an important element in sonodynamic therapy, which can maximize the effects of ultrasonic irradiation. Sonosensitizers have achieved rapid development in the past decades, based on the known mechanisms of cell apoptosis or cell death induced SDT. Moreover, the selection of a suitable sonosensitizer in carrying out SDT on cancers has become an important issue in current investigations.

Modulation effects of SDT on Cancer microenviroment

Cancer microenvironment describes cellular environments in which the tumor exists. It includes surrounding blood vessels, fibroblasts, immune cells, bone marrow-derived inflammatory cells, signaling molecules, lymphocytes, and the extracellular matrix. The surrounding microenvironment and the tumor are intimately related and interact constantly. While the tumor microenvironment provide the support for the growth and metastasis of cancer cells, the tumors can influence the microenvironment by releasing extracellular signals, promoting tumor angiogenesis and inducing peripheral immune tolerance,. Recently, several investigations have showed that sonodynamic therapy can efficiently modulate the tumor microenvironment.

A significant body of data has demonstrated therapeutic effectiveness of sonodynamic therapy in cancer treatment. In view of the significant depth that ultrasound penetrates tissue, sonodynamic therapy provides an advantage over photodynamic therapy, in which less penetrating light is employed. More work needs to be done before sonodynamic therapy is accepted as an adjuvant or replacement method for traditional cancer treatment. More data necessary to ascertain the actual anticancer activities of sonodynamic therapy will be acquired in the near future.

Innovations & Future Opportunities in Radio Frequency Identification (RFID) Technology

Radio frequency identification (RFID) has made remarkable progress since it was generated. With a huge potential, today, RFID technology has become one of the most blooming technology with numerous applications. When RFID technology is mixed with printing technology, new and better opportunities are created. While printing an entire RFID chip and antenna has become possible to print, still RFID technology is considered impractical for real world application.

Radio frequency identification (RFID) is a method of communicating data between an electronic tag and a reader with radio waves, and this technology is generally used for tracking and identification purposes. Currently some of the major areas for RFID are in public inventory tracking, transportation, animal identification, logistics, and asset management. RFID technology is so competent and beneficial that a few companies are initiating measures to make a requirement for its suppliers in order to participate in an RFID system. Adding of the printing technology is believed to be the key method for future innovation in RFID technology.

New Opportunities in RFID Technology

When electronic tag is directly put onto a product, it gives way to ideas such as smart cards, smart labels, and smart packaging and these ideas rely on RFID technology to create a system to replace barcodes. Printing the antenna that extends the radio waves transmitted and reduces cost by eliminating the previous method of etched antenna is currently the actual printing portion of RFID technology. The electronic tag or chip is attached once the antenna is printed.

If we talk about the market for RFID printing, it is small due to the expense of the process and materials. Even with the reduction in cost with a printed antenna, the process is currently is a bit expensive, but necessary majors are been taken to make it cheaper. What poses a great challenge for printing technology is to make possible that the chip could be printed as well as the antenna. Once the necessary technology for RFID printing exists, there will be an outburst of opportunities in new markets.

Printed RFID Tags

One of the most innovative and useful labeling and product tracking RFID technology is RFID printers. The current theory on RFID printers is based on carbon nanotube technology. The carbon nanotubes are infused with ink and printed on using inkjet technology, which is a printing process where very fine ink droplets are sprayed in a controlled manner on to a substrate or printing surface. There is an ability to print thin film transistors with the help of inkjet printing process and carbon nanotube infused ink combined, which is indeed there is a key element in RFID printers. These printable transistors can be printed on paper or plastic.

With the emerging RFID technology, the future for printed RFID tags become clearer. Though there are several obstacles blocking the success of printed RFID tags, the thrilling potential of RFID technology is uncovering the advancements in printed RFID tags

Know How Facebook is Turning Tables for Businesses

There is no doubt in the fact that Facebook is one of the most popularly used social media platforms, which makes it a must have when it comes to running businesses. Having tremendous potential for growth, Facebook allows businesses to spread like wild fire amongst the billion Facebook users worldwide. So how is this social media platform impacting the success of businesses?

Being the largest social media platform, Facebook allows businesses to connect with more people and increase visibility amongst the users. According to the recent trends, social media is better and more advanced compared to traditional marketing to enhance the way businesses interact with their audiences. This approach is a clear representation of the businesses that adapt to social trends followed by their audiences to achieve complete visibility.

Facebook community plays an important role in growth of small businesses

An event held in Phoenix, threw light on the aspects of Facebook community boost that could help transform how small businesses fulfill their business goals. The process of building social connections with the prospects is a great way of branding and spreading information related to the businesses. The extensive use of platforms like Facebook could help reduce advertising costs for small businesses as they would not find the need to travel or print flyers and posters. Besides, Facebook’s altogether different and well equipped functionality for business owners, gives them the freedom to utilize the tools for greater enhancement of business.

Social media marketing has changed the way people do business, as the strings of recommendations and referrals are in the customer’s hands, which help the business grow massively. With more engagements with the customers, businesses can use Facebook for branding purposes. Facebook could also help the businesses understand and know their customers well, with the kind of products posts they like and share along with their friends. This approach helps build a good social media marketing strategy for the future.

Going beyond the traditional concept of connecting with people around, Facebook is now transforming and digitizing businesses to channelize their resources rightly. What better than connecting with the audience without physically interacting with them? Facebook is all set to turn the tables for businesses, giving them more opportunities and tools to connect better as well as helping the audiences know more about their ideal and best-loved products just by surfing their favorite social networking site.

‘Digital Humans’ to Redefine Virtual Assistance

The intervention of technology in traditional processes has given rise to several new innovations and changes being made in the way businesses operate. The digital world is often seen challenging companies to cope with the requirements of enhanced technologies. With technologies like virtual assistance, chatbots, and online query resolving systems, businesses are trying to increase the number of queries attended and improve the overall experience they deliver to customers. Virtual assistance that is digitally-enabled, is an intelligent software service that enhances the traditional capabilities of human assistance with a unique set of features. ‘Digital humans’ is the next-level innovation in the umbrella of this cutting- edge technology that takes virtual assistance to greater heights.

ANZ Bank to realize the potential of ‘Digital Human’

ANZ Bank recently announced that their new digital assistant, ‘Jamie’, developed in partnership with Soul Machines, which will be deployed this week, helping bank customers with support and general queries. The bank is all set to revolutionize the banking experience that they provide to their customers. This astonishing digital human is well programmed to resolve frequently received queries to ensure that they could provide initial support to the customers that face any banking dilemmas.
They believe that this system would be an emotionally intelligent solution making it more interactive as compared to the chatbots.
Powered by an AI engine, it is capable of responding to human emotions along with queries. This way ‘Jamie’ has the exceptional ability to provide an immersive experience that actively engage with the customers senses. Their advancements allow them to self-learn from the previous conversations, making them more equipped with the requirements of the customers.

Digital Human: Umpqua Bank’s new innovation strategy

The physical retail banking experience and digital innovation together would be termed as a ‘digital human’. These are the words of the new CEO of Umpqua Bank, Cort O’Haver, who is all set to transform the bank’s customer experience by giving it a digital face. The team is currently working on a new app that lets customers chat with the bank specialists in order to resolve any issues on the user side.

Going beyond the horizon of mere voice and typed chatbots, this technology helps businesses to be open for newer opportunities in the field of AI-driven virtual assistance. This encourages the customers to be more engaged, resulting in knowing the customers behavior and patterns in a better manner.
The evolution of virtual assistance is quick and allows users to have a more customized experience that helps their work to be done in greater speed. яндекс