Glycoprotein is the proteins with oligosaccharide moieties which emerge after glycosylation during post-translational or co-translational modification of proteins.
Glycoprotein plays a crucial role in cellular metabolism and functions including cell signalling, cellular adhesion, immune system, pathogenicity, genesis and progression of metabolic disease and biomarker of diseases such as cancer.
There Glycosylations are of two types, O-glycosylation on Serine (Ser) or Threonine (Thr) residues and N-glycosylation on Aspargine (Asn) residue with the consensus sequence of Asn-X-Ser, where X is any amino acid except proline (Pro).
Glycoprotein analysis can be instrumental for understanding its structure and function and its role in the underlined diseases prognosis and their therapy. The global glycoprotein analysis market is anticipated to grow with the advancing research of glycoprotein into chronic diseases.
Coronavirus has leveraged the global glycoprotein analysis market growth. Coronavirus glycoprotein coat is actively dwelled to decode the pathogenicity and develop vaccine or therapies for the novel-virus.
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Immunoblotting analysis, epitope mapping, chromatography, spectrometry and many others are actively implemented for research and glycoprotein analysis
Glycoprotein Analysis Market: Drivers and Restraints
The global glycoprotein analysis market driver includes the massive research and technology for glycoprotein analysis to unravel their structure and function. Glycoprotein analysis has a huge market base in food consumption bacterial and yeast protein production and healthcare.
Also the advancing R&D technology and investments into glycoprotein analysis for drugs therapies vaccines disease progression understanding the biology of glycoprotein and product launches.
Glycoprotein analysis is has massive rseaech involvement into cancer of breast prostate and ovary malfunctioning glycoprotein associated enzyme and metabolism aberrations resulting in glycoprotein storage diseases including Alpha-Mannosidosis Aspartylglucosaminuria and Beta-Mannosidosis.
Glycoprotein analysis has attracted huge R&D investments subsidization and reimbursements for glycoprotein associated antibodies mutations and associated pathway targeting which altogether propels the glycoprotein analysis market growth.
However the smooth growth of glycoprotein analysis market is halted due to low abundance of native target glycoproteins purification enrichment and fractionation issues simultaneous glycoprotein sequencing glycan moieties and glycosylation sites analysis.
Glycoprotein analysis gets complex due to the increasing heterogeneity of glycan structures. Glycoprotein analysis requires further sensitive and quantitative methods for the urgent detection of specific glycoform and its role in disease progression.
Glycoprotein analysis techniques such as spectroscopy and chemical reagents are expensive labour-intensive and the dearth of research and medical professionals decelerates the growth of glycoprotein analysis market.
Despite these constraints global glycoprotein analysis market is poised to grow lucratively due to the progressing R&D and healthcare and investments driven by the vast application of glycoprotein in healthcare and food.
The novel analysis methods with improved accuracy sensitivity and efficacy and cost-effectiveness which will propel the global glycoprotein analysis market furthermore.
Glycoprotein Analysis Market: Overview
The global glycoprotein analysis market is growing lucratively with the technological advancements of glycoprotein analysis for research healthcare and food. By glycosylation the global glycoprotein analysis glycosylation is divided into N-linkage and O-linkage which have a crucial role in the progression and therapy of several diseases.
N-glycosylation plays crucial role in arthritis cancer diabetes Crohn’s diseases and several nervous system diseases. N-linked glycoprotein is found in therapeutic antibodies including Rituximab Etanercept and Infliximab. O-glycosylation is involved in antibody structure analysis and development targeting of Alzheimer diseases and cancers by O-glycan structure and terminal Lewis epitopes.
By end-users the global glycoprotein analysis techniques have major contributions from hospital and research institutes and their collision for glycoprotein associates diseases diagnosis and analysis. The glycoprotein analysis data from research institutes are crucial for the diagnosis.
By techniques mass spectrometry dominates the glycoprotein analysis technique due to their sensitivity specificity speed and stoichiometry for the glycoprotein identification glycosylation site and glycan structures.
Major spectrometry techniques for glycoprotein analysis include mass spectrometry (MS) Electrospray ionization mass spectrometry (ESI-MS) matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) and hydrophilic interaction chromatography-mass spectrometry (HILIC-MS).
Glycoprotein Analysis Market: Regional Outlook
North America holds the largest global glycoprotein analysis market with its advanced R&D pharmaceutical development and research healthcare expenditure and investments which are supported by the government research institutes hospitals and other organizations for disease diagnosis therapy and glycoprotein food industry and key players.
Europe holds the second largest global glycoprotein analysis market with its advanced research and healthcare government’s support numerous start-ups and leading companies.
Asia-pacific glycoprotein analysis market is growing at the fastest pace fuelled by the advancing research institutes and hospitals progressing pharmaceuticals and glycoprotein analysis and production. Latin America glycoprotein analysis market is growing gradually with improving R&D and healthcare.
MEA& Africa glycoprotein analysis market is growing laggardly due to the technological backwardness although South-Africa and Israel with their advancing research and growing protein industry are expected to push the growth of regional glycoprotein analysis market
Glycoprotein Analysis Market: Key Players
The key players of the global glycoprotein analysis market include
- Sigma-Aldrich. BD
- Enzo Life Sciences
- Creative Diagnostics
- Thermo Fisher Scientific
- Epitope Diagnostics Inc.
- R&D Systems
- QED Bioscience Inc
- ACROBiosystems.
The research report presents a comprehensive assessment of the market and contains thoughtful insights facts historical data and statistically supported and industry-validated market data.
It also contains projections using a suitable set of assumptions and methodologies. The research report provides analysis and information according to market segments such as geographies application and industry.
The report covers exhaust analysis on:
- Market Segments
- Market Dynamics
- Market Size
- Supply & Demand
- Current Trends/Issues/Challenges
- Competition & Companies involved
- Indication
- Value Chain
Regional analysis includes:
- North America (U.S. Canada)
- Latin America (Mexico. Brazil)
- Europe (Germany U.K France Italy Spain)
- South Asia (India ASEAN Countries)
- East Asia (Japan China & South Korea)
- Oceania (Australia & New Zealand)
- Middle East and Africa (GCC Countries South Africa Northern Africa)
The report is a compilation of first-hand information qualitative and quantitative assessment by industry analysts inputs from industry experts and industry participants across the value chain.
The report provides in-depth analysis of parent market trends macro-economic indicators and governing factors along with market attractiveness as per segments. The report also maps the qualitative impact of various market factors on market segments and geographies.
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Report Highlights:
- Detailed overview of parent market
- Changing market dynamics in the industry
- In-depth market segmentation
- Historical current and projected market size in terms of volume and value
- Recent industry trends and developments
- Competitive landscape
- Strategies of key players and products offered
- Potential and niche segments geographical regions exhibiting promising growth
- A neutral perspective on market performance
- Must-have information for market players to sustain and enhance their market footprint
Glycoprotein Analysis Market: Segmentation
The global glycoprotein analysis market is segmented into glycolysation, end-users, techniques and regions.
By glycolysation
- N-linkage
- O-linkage
By end-users
- Hospital
- Research Institutes
- Others
By techniques
- Molecular Reagents
- Mass Spectrometry