As per Future Market Insights (FMI) – a well-known name in market research, the global preparative and process chromatography market is expected to grow at a steady pace through 2030.
The noteworthy trends witnessed by the preparative and process chromatography market are an ever-increasing demand for monoclonal antibodies, growing adoption of advanced chromatic techniques in the biotechnology industries, and enhanced drug assessment techniques.
The advances in scientific understanding, analytical capabilities, and computational power have enabled a mechanistic modeling with respect to biotechnology.
As such, industrially relevant monoclonal antibody-cation exchange (CEX) chromatography processes have been doing the rounds.
This antibody purification process has been reported to be extra effective in removal of high molecular weight species along with elimination of HCPs (host cell proteins) and DNAs.
This process has, in actual sense, revolutionized the way of process development. This inclination is expected to drive the process chromatography in future as well.
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Key Takeaways from Preparative and Process Chromatography Market Study
- Centrifugal Partition Chromatography to gain center-stage between 2020 and 2030
- Gas chromatography to hold a prominent share in the forecast period
- Simulated Moving Bed (SMB) chromatography to be a key growth driver in the forecast period
- Asia-Pacific projected to witness the highest CAGR in the preparative and process chromatography market in the forecast period
- Increase in demand for omega-3 fatty acids to be a key growth driver
- North America held the largest market share in 2019 and will continue to dominate the market in the forecast period
FPLC v/s HPLC
HPLC, as the name suggests, uses high pressure of up to 1200 bar, whereas FPLC counts on low pressure – as low as 30 bar. This could be attributed to the fact that column matrices and biomolecules are fragile and found to be stable only at low pressure.
Besides, FPLC implies using saline buffers for averting biomolecules’ denaturation. However, utmost care needs to be taken to see that stainless steel is not used, so that corrosion could be prevented.
FPLC is further classified into HIC (Hydrophobic Interaction Chromatography), SEC (Size Exclusion Chromatography), AC (Affinity Chromatography), and Ion-Exchange Chromatography.
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FMI gives a comprehensive study of preparative and process chromatography market based on type (preparative chromatography (Consumables, columns, systems, services, resins) and process chromatography (consumables, columns, systems, services, resins), end-use (biotechnology & pharmaceutical industry, food & nutraceutical industry, academic research laboratories) across seven geographies.
Also, the fact that the highest number of diabetic patients are housed in China and India is driving the importance of preparative and process chromatography herein. At the same time, high cost of the instruments acts as a major restraint.
Key Segment
Product Type
- Preparative
- Consumables (Columns, Chemicals and Reagents, Resins)
- Systems
- Process
- Consumables (Columns, Chemicals and Reagents, Resins)
- Systems
End-User
- Biotechnology & Pharmaceutical Industry
- Food & Nutraceutical Industry
- Academic Research Laboratories
Region
- North America
- Latin America
- Europe
- East Asia
- South Asia
- Oceania
- Middle East and Africa