Chromatography is the technique used for the separation of components of a mixture. The separation technique uses the principle that different amounts of each solute are distributed in different proportions between a moving fluid stream, and an adjoining stationary phase. The moving stream is called the mobile phase.
The mixture to be separated is dissolved in a fluid known as the mobile phase, which carries the mixture through a structure containing another material known as the stationary phase, where chromatography silica resins come into use. Different constituents of a mixture travel at different speeds and this information is used to separate the constituents. The separation is brought about using differential partitioning between mobile and stationary phases. In column chromatography, chromatography silica resins are used as adsorbents and are generally packed in a glass column.
Chromatography silica resins find application during the stationary phase. They are also used in normal phase chromatography. Chromatography silica resins come in a range of shapes and sizes. The most common grades of chromatography silica resins are mesh 70 – 230 (63 – 200 µm) for gravity column chromatography and mesh 230 – 400 (40 – 63 µm) for flash column chromatography.
Considering the vital applications of chromatography silica resins, the study of the global chromatography silica resin market becomes an important read.
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Chromatography Silica Resins Market: Key Trends, Drivers
Specific features of chromatography silica resins prove to be quite useful during the separation process. For instance, it has been found that high purity chromatography silica resins provide consistency, reliability and reproducibility vis-à-vis other chromatography resins.
Chromatography silica resins make it possible to eliminate contamination, lower back pressure and facilitate superior separation. Consistency in the manufactured lots of chromatography silica resins, along with their narrow particle and pore-size distribution enhances the process of chromatography. Also, chromatography silica resins provide reliable chromatography for optimal separation and resolution.
As chromatography silica resins display desired characteristics for chromatography applications such as symmetrical peaks with no tailing, low metal content, neutral pH & controlled water content, high surface area and density and possess superior loading capacity which enables added silica quantity for the same volume along with solvent economy (smaller dead volume), they have been gaining increasing preference over other chromatography resins. These factors, combined together, are expected to drive the market demand for chromatography silica resins across the globe.
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The steady growth of the pharmaceutical and biotechnology industry is expected to fuel the growth of global chromatographic silica resin market over the forecast period as these resins find large scale applications in the pharmaceutical industry where they are used to segregate and collect different components of drugs. Some of the antibiotics produced using this method of purification include rosarimicin, coloradocin and benzanthrins, among others. These resins are also employed in the study of medicines such as hypnotics, sedatives, analgesics, local anaesthetics and steroids.
However, end-users have been finding attractive substitutes for chromatography silica resins. For instance, activated alumina is known for relatively superior separation and purification characteristics. Unlike chromatography silica resins, the atmospheric properties of alumina makes it workable with neutral, acidic and basic compounds. Similarly, silica gel can also be used in limited end use industries. Alumina, however, being a superior ingredient is used in many environmental cleanup procedures. These factors are expected to restrain the market growth of chromatography silica resins in the next few years.
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Chromatography Silica Resins : Market Participants
Examples of the market participants in the global chromatography silica resin market are as follows:
- Sigma-Aldrich Co. LLC.
- Sorbead India
- Sorbent Technologies, Inc.
- Sisco Research Laboratories Pvt. Ltd.
- Material Harvest
- Shimadzu Corporation
- SiliCycle Inc.
- Fuji Silysia Chemical Ltd.
- Alfa Aesar, Thermo Fisher Scientific.
- Osaka Soda
The research report presents a comprehensive assessment of the market and contains thoughtful insights, facts, historical data, and statistically supported and industry-validated market data. It also contains projections using a suitable set of assumptions and methodologies. The research report provides analysis and information according to market segments such as geographies, application, and mesh size, particle size, etc.