Nasal vaccines Market Trends, Strong Application Scope, Key Players, Growth Overview and Forecast by 2030

Nasal vaccines are the administration of mucosal vaccines through nasal route using a nasal sprayer or intra-nasal drop.  Mucosal infections are caused by several groups of bacteria and viruses.

Mucosal immunization is advantageous than the conventional administration routes due to the induction of both systemic and mucosal immune responses, additional pathogen protection by mucosal secretory IgA antibodies at entry site and its non-invasive nature.

According to the Forum of International Respiratory Societies, lower respiratory tract infection and pneumonia claim 4 million lives every year. World Health Organization (WHO) stated, over 3 to 5 million hospitalized and 0.2 million deaths reported due to influenza.

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Nasal vaccines, due to their non-invasiveness, easy access and better immunization are emerging as viable administration alternate to oral or intramuscular administrations. Nasal vaccines may confer protection to the mucosa of lungs, genital tract and intestines.

The global nasal vaccines market is lucrative and is anticipated to register to boost growth with the progressing R&D, Coronavirus emergence, past paced clinical trials and increasing prevalence of other respiratory infections.

Surging cases of respiratory infections such as Streptococcus, Enterobacteriaceae, and viral such as Haemophilus influenza, Coronavirus, Adenovirus and others are propelling the nasal vaccines market growth. Also, the advantageous properties of nasal vaccines, increased compliance, key players and R&D progress are promoting the market growth.

Nasal vaccines emerges as a viable vaccine delivery alternate due to its non-invasiveness, better absorption in microvilli surface, protection from infection at entry site and elicits both mucosal systemic immune response. Drug manufacturers are working with the novel strategy of nasal vaccines development including live-attenuated-pathogen, adjuvants, nanoparticles, mucoadhesives, viruses-like-particles, DNA-vaccines and lipid-based-particulates.

However several challenges constraints the nasal vaccines market growth such as restricted delivery volume (up-to 25 to 200 microlitre), limited efficacy and altered drug permeability due to mucociliary activities, poor antigen retention, limited compatible adjuvants, adverse reactions including mild fever and ache.

The key players of nasal vaccines market include

  • Sanofi
  • AstraZeneca
  • Abbott
  • GlaxoSmithKline
  • Serum Institute of India
  • Bharat Biotech
  • Antares Pharma
  • INJEX Pharma GmbH
  • BioDiem

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