As the need for whole genome amplification (WGA) in forensics and genetic disorders grows, the whole genome amplification market is predicted to exceed US$ 5.5 billion by the end of 2033, according to Future Market Insights (FMI) in its market analysis.
Sales of whole genome amplification are expected to reach $2.8 billion by 2023. Between 2023 and 2033, the worldwide whole genome amplification market is expected to grow at a 7.0% CAGR.
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It also catches the chromosomal DNA of these single cells after extraction, which is then fixed in the micropillar array to allow for isothermal amplification. ‘On-chip cell capture and DNA extraction’ is the name given to the complete procedure.
As standard single cell WGA is frequently prone to amplification biases, which may have a major impact on the accuracy of single cell sequencing results.
This disadvantage is expected to be overcome with the advent of single cell on-chip WGA, which will result in lower amplification biases and improved genome coverage. Individual cancer cell genomes (human) taken from the HeLa Cell Line were utilised by the researchers.
WGA is an important method for analysing DNA from small amounts of genomic DNA. The convenience of use given by various WGA kits for the entire process has driven the market throughout the years.
Increasing research efforts will continue to be a driving force in the growth of the whole genome amplification market over the next decade. Adoption of this process is predicted to rise rapidly, primarily among research institutes, hospitals, diagnostic centres, and forensic labs, because it provides a more advanced method of genome amplification and sequencing.
Molecular testing firms are focused increasingly on the development of new devices and kits, such as WGA kits and complete WGA kits with improved capabilities, in order to increase their revenue share.
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Single Cell WGA Continues to Bring in New Applications
The introduction of massively parallel single-cell genome sequencing is expected to expand our understanding of genetic diversity in complex biological systems.
Single cell WGA is a technique for examining sequence information from a single cell using improved next generation sequencing technology. This approach is regarded as a powerful tool for understanding genetics by bringing the full genome structure to a cellular level.
Because this method provides a high-resolution image of the genomic material, its use will grow in a variety of biological domains, including microbiology, immunology, neuroscience, cancer research, and tissue mosaicism.
The key players of the market, including GE Healthcare, Sygnis AG, Illumina, Inc., Merck KGaA, Thermo Fisher Scientific Inc., and Active Motif are inclined more towards strategic acquisitions and mergers.
They are also looking for distribution and collaboration agreements to help improve their product reach. It will also help them serve end users better, with diagnostic consulting and good laboratory practices. High price point may remain a major challenge for companies.
Key Segments Covered in Whole genome amplification Market Study
By Product Type
- Single Cell WGA Kit
- Complete WGA Kit
- WGA Re-Amplification Kit
- WGA & Chip DNA Kit
- Others
By Application
- Drug Discovery & Development
- Disease Diagnosis
- Agriculture & Veterinary
- Research
- Forensics
- Others
By End User
- Pharma & Biotech Companies
- Hospitals & Clinics
- Contract Research
- Organizations
- Research & Academic Institutes
- Others
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Future Market Insights (ESOMAR certified market research organization and a member of Greater New York Chamber of Commerce) provides in-depth insights into governing factors elevating the demand in the market. It discloses opportunities that will favor the market growth in various segments on the basis of Source, Application, Sales Channel and End Use over the next 10-years.
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