Innovative Approaches to Myelofibrosis Treatment | Combining JAK Inhibitors for Improved Patient Outcomes

 

Myelofibrosis Treatment Market Sales is predicted to increase at a CAGR of 5.5% between 2023 and 2033, reaching US$ 1,280 million in 2033, according to Future Market Insights. From 2018 through 2023, sales increased at a CAGR of 5.2%.  Depending on their condition and symptoms, patients with Myelofibrosis can be treated utilising a variety of approaches. Chemotherapy, targeted medication therapy, surgery, radiation therapy, and stem cell transplants are among the treatment options available. JAK inhibitors, as well as JAK inhibitor combination treatments in the first and second lines of treatment, may be included in future Myelofibrosis treatment options.

Janus-associated kinases (JAKs) are proteins that are present in Myelofibrosis. There will also be a review of upcoming JAK inhibitor therapy and non-JAK inhibitor therapy, with a focus on the new difficulty of moving from one JAK inhibitor medication to another. Future medicines in this field are eagerly expected, as are new JAK inhibitor and non-JAK inhibitor medications.

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The normal therapy goals are to diminish splenomegaly and disease-related symptoms, limit complications such as thrombosis and haemorrhaging, and, ideally, slow disease progression. As the number of available medications for the treatment of Myelofibrosis has risen over the last decade, therapeutic techniques have primarily focused on symptom management.

Key Takeaways from the Market Study

  • By 2023, the global market for Myelofibrosis is expected to reach $749.05 billion.
  • North America, which has a well-established healthcare system and a high awareness of cancer sufferers, is predicted to represent 53% of the worldwide healthcare market in 2023.
  • During the projection period, the European region is likely to lead the global market for myelofibrosis treatments, accounting for 42% of the market.
  • The market for chemotherapy is predicted to develop based on the type of myelofibrosis treatment.
  • During the projected period, the oral route of administration is expected to expand at a revenue share of 38%.

“New oral drugs and devices are being approved as chronic cancer becomes more prevalent, and artificial intelligence and technology will play a significant role in growing drug delivery methods.” comments a Future Market Insights analyst. 

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Competitive Landscape 

Many companies are expected to focus their efforts on developing innovative diagnostic techniques in the near future, resulting in the expansion of their product lines, the acquisition of other companies, and the merger of their companies.

  • Karyopharm Therapeutics Inc., a commercially-stage pharmaceutical company developing novel cancer treatments, will host a webcast at the 64th American Society of Haematology (ASH) Annual Meeting and Exposition to provide updates on the Phase 1 open-label, ruxolitinib combination study in untreated Myelofibrosis patients.
  • CTI BioPharma Corp. will offer two oral presentations and a poster session concerning its pacritinib programme at the 64th American Society of Haematology (ASH®) Annual Meeting and Exposition in New Orleans, Louisiana and virtually from December 10-13, 2022. PERSIST-2, a Phase 3 study of pacritinib, a novel JAK2/IRAK1 inhibitor approved by the FDA for the treatment of severe thrombocytopenia (platelets less than 50 x 109/L) in Myelofibrosis patients, demonstrates the drug’s potential anaemia benefit by inhibiting Activin A receptor type 1 (ACVR1).

Major Players

  • Pfizer Inc.
  • F. Hoffmann-La Roche Ltd
  • Mylan N.V.
  • Fresenius Kabi AG
  • Hikma Pharmaceuticals PLC
  • Novartis AG
  • Teva Pharmaceutical Industries Ltd.
  • Bristol Myers Squibb Company

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More Valuable Insights 

Future Market Insights, in its new offering, presents an unbiased analysis of the global Myelofibrosis market, presenting historical analysis from 2017 to 2023 and forecast statistics for the period of 2023 to 2033.

Key Segments Profiled in the Myelofibrosis Market Industry Survey?

By Treatment Type:

  • Targeted Therapy
  • Chemotherapy
  • Others

By Route of Administration:

  • Oral
  • Parenteral
  • Others

By End User:

  • Hospitals
  • Homecare
  • Specialty Clinics
  • Others

By Distribution Channel:

  • Hospital Pharmacy
  • Online Pharmacy
  • Retail Pharmacy

About Future Market Insights, Inc.

Future Market Insights, Inc. (ESOMAR certified, Stevie Award – recipient market research organization and a member of Greater New York Chamber of Commerce) provides in-depth insights into governing factors elevating the demand in the market. It discloses opportunities that will favor the market growth in various segments on the basis of Source, Application, Sales Channel and End Use over the next 10-years.

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