In the dynamic world of biopharmaceuticals and industrial biotechnology, the Downstream Processing Market plays a crucial role in extracting, purifying, and refining valuable bioproducts. This often overlooked yet vital step ensures that biopharmaceuticals, enzymes, biofuels, and other biotechnological products reach consumers with optimum quality and efficiency. As the biotech industry continues its rapid expansion, downstream processing is poised to witness significant growth and innovation.

Downstream processing involves a series of sophisticated techniques designed to isolate and purify desired biomolecules from complex mixtures obtained during fermentation or cell culture processes. The process encompasses numerous purification steps, including separation, filtration, chromatography, and drying, among others. Through these steps, impurities are removed, and the desired biomolecules are concentrated to achieve the desired quality and potency.

Several factors are driving the growth of the downstream processing market. Firstly, the increasing demand for biopharmaceuticals, driven by aging populations and the prevalence of chronic diseases, is creating a burgeoning market for downstream processing solutions. Additionally, advancements in biotechnology and genetic engineering have led to the development of novel bioproducts, further fuelling the demand for efficient downstream processing technologies.

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By the end of 2032, the market for downstream processing is expected to be worth US$ 72.3 billion, growing at a CAGR of 11.3% between 2022 and 2032. The size of the worldwide downstream processing market was estimated at US$ 22.0 billion in 2021, and by the end of 2022, it is predicted to reach US$ 24.9 billion.

Moreover, stringent regulatory requirements for the approval of biopharmaceuticals and biotechnological products necessitate high-quality downstream processing to ensure product safety and efficacy. This has prompted biotech companies to invest in state-of-the-art downstream processing facilities and technologies.

Forecast Highlights on Global Downstream Processing Market

  • As per the forecast of Future Market Insights, the filters product type segment is slated to touch a value of nearly US$ 5,700 Mn in the year 2022. This represents a robust CAGR during the assessment period of 2017-2022. The filters product type segment is estimated to account for more than one-fifth of the revenue share of the product type segment by the year 2017 and is forecasted to lose market share by 2022 over 2017.
  • As per the forecast of Future Market Insights, the contract manufacturing organizations segment will reach a value of nearly US$ 5,500 Mn in the year 2017. This represents a robust CAGR growth during the forecast period. The contract manufacturing organizations segment is forecasted to account for more than one-third of the total revenue share of the end users segment by the end of the year 2017 and is expected to lose in market share by 2022 as compared with the year 2017.
  • As per the forecast of Future Market Insights, the monoclonal antibody production segment is slated to reach a value of about US$ 8,300 Mn in 2022. The monoclonal antibody production segment is expected to gain market share by the end of the year 2022. The largest share is contributed by the North America region in the monoclonal antibody production segment.
  • Future Market Insights forecasts the gel chromatography segment to exhibit a compound annual growth rate (CAGR) of nearly 15.0% from 2017 to 2022.

The report has also included the profiles of some of the leading companies in the downstream processing market like Sartorius Aktiengesellschaft, Repligen Corporation, Merck & Co Inc., Thermo Fisher Scientific, Inc., Eppendorf AG, General Electric Company, Corning Incorporated, 3M Company, Lonza Group Ltd. and Danaher Corporation.

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Market Taxonomy

Product Type:

  • Chromatography Columns and Resins
  • Membrane Adsorbers
  • Single-use Products
  • Consumables and Accessories

End Users:

  • Biopharmaceutical Manufacturers
  • Contract Manufacturing Organizations (CMOs)

Applications:

  • Monoclonal Antibody Production
  • Vaccine Production
  • Insulin Production
  • Immunoglobulin Production
  • Erythropoietin Production
  • Other Application

Technology:

  • Gel Chromatography
  • Ion Exchange Chromatography
  • Affinity Chromatography
  • Hydrophobic Interaction Chromatography
  • Tangential Flow Filtration
  • Centrifugation
  • Others

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Region:

  • North America
  • Latin America
  • Europe
  • Japan
  • Asia Pacific excluding Japan
  • Middle East and Africa

About Future Market Insights (FMI)

Future Market Insights, Inc. (ESOMAR certified, recipient of the Stevie Award, and a member of the Greater New York Chamber of Commerce) offers profound insights into the driving factors that are boosting demand in the market. FMI stands as the leading global provider of market intelligence, advisory services, consulting, and events for the Packaging, Food and Beverage, Consumer Technology, Healthcare, Industrial, and Chemicals markets. With a vast team of over 5000 analysts worldwide, FMI provides global, regional, and local expertise on diverse domains and industry trends across more than 110 countries.

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