The global PCSK9 inhibitors market is on pace for impressive growth, with 2024 revenues expected to surge to US$ 2,733.7 million. Forecasted to expand at a remarkable compound annual growth rate (CAGR) of 18.7% until 2034, the market is expected to peak with total sales of US$ 15,140.3 million, indicating the rising need for novel treatments to lower cholesterol.
The evolocumab segment is expected to hold a dominant 71.3% value share in the PCSK9 inhibitor market by 2024. Nonetheless, the inclisiran market is poised for remarkable expansion, as sales are expected to rise at an astounding rate of 31.3% CAGR throughout the evaluation period, highlighting its increasing popularity in the treatment market.
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Key Takeaways:
- The global PCSK9 inhibitor market is projected to reach US$15.14 billion by 2034, reflecting a remarkable CAGR of 18.7%.
- This surge is driven by a significant year-over-year growth of 21.5% in 2024, highlighting the rapid expansion of the market.
- Evolocumab is currently the dominant player, but inclisiran is poised for the fastest growth, with a projected CAGR of 31.3%.
Competitive Landscape:
Clinical trials can serve as a powerful promotional strategy for a company, offering a multifaceted approach to showcasing its commitment to innovation, patient care, and scientific advancement. Securing approval from the U.S. Food and Drug Administration (FDA) is a significant achievement for any pharmaceutical or biopharmaceutical company.
Top manufacturers of PCSK9 inhibitors are heavily investing in research and development to explore novel treatment approaches for high cholesterol. For instance, they are exploring combination therapies with other cholesterol-lowering drugs to broaden the application of PCSK9 inhibitors and improve patient outcomes.
Recent Developments in the PCSK9 Inhibitor Market
- In April 2021, Praluent (alirocumab) injection was approved by the Food and Drug Administration (FDA) for patients with homozygous familial hypercholesterolemia (HoFH).
- In November 2023, LIB Therapeutics completed the global phase 3 LIBerate program of Lerodalcibep, a new third-generation PCSK9 inhibitor in development for cardiovascular diseases.
- In August 2023, Merck initiated the Phase 3 clinical program for oral PCSK9 inhibitor candidate MK-0616. The oral PCSK9 inhibitor (MK-0616) is being evaluated for the treatment of adults with hypercholesterolemia.
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Key Players in the PCSK9 Inhibitor Market Include:
- Novartis AG
- Regeneron Pharmaceuticals, Inc. (Sanofi)
- Amgen Inc.
- Innovent
- LIB Therapeutics, LLC
- Shanghai Junshi Biosciences Co., Ltd
- Merck & Co., Inc.
- AstraZeneca
Key Market Segments Covered in PCSK9 Inhibitor Industry Research:
By Drug:
- Alirocumab
- Evolocumab
- Inclisiran
- Tafolecimab
By Modality:
- Fully-humanized monoclonal antibodies
- siRNA
By Indication:
- Primary Hyperlipidemia
- Familial Hyper Cholesterolemia
- Prevention of Other Cardiovascular Events
By Sales Channel:
- Hospitals
- Specialty Clinics
- Retail Pharmacies
- Online Pharmacies
By Region:
- North America
- Latin America
- East Asia
- South Asia & Pacific
- Western Europe
- Eastern Europe
- Middle East & Africa
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