The global Graft Versus Host Disease (GvHD) Treatments market is set for robust growth, with projections indicating it will reach a valuation of USD 5,960.7 million by 2033. This expansion is expected to occur at a compound annual growth rate (CAGR) of 8.2%.
In 2023, the GvHD treatment market is valued at approximately USD 2,713.6 million. This growth trajectory has been consistent, reflecting an 8.2% CAGR from 2018 to 2022. The market’s steady ascent is attributed to the increasing adoption of corticosteroids and combination therapies for treating graft-versus-host disease in hematopoietic cell transplant (HCT) patients.
Allogeneic hematopoietic cell transplantation (HCT), commonly referred to as stem cell transplantation, is associated with a potentially lethal side effect called Graft Versus Host Disease (GvHD). The global market for GvHD treatments is expanding quickly as a result of improvements in treatment choices and the rising incidence of GvHD.
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In December 2021, the US Food and Drug Administration approved Orencia (abatacept) for the management of GVHD in both adult and pediatric patients. Orencia is used to avoid autoimmune diseases as well as treat them. Through specific attachment to and modification of one of the key costimulation signals sent by these cells, this medicine circumvents the attack of T-cells, which are essential in acute GVHD.
As a result, T-cells are prevented from fully activating, hence preventing acute (GVHD). Surgeons are evaluating several new approaches to prevent (GVHD) in the future.
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Key Takeaways:
- The global graft versus host disease (GvHD) treatment market is expected to reach US$5.96 billion by 2033, growing at a CAGR of 8.2%.
- Rising adoption of combination therapies and advancements in allogeneic hematopoietic cell transplant (HCT) are key growth drivers.
- Newer medications like Jakafi and Rezurock offer improved efficacy for chronic GvHD compared to traditional treatments.
Recent improvements in acute graft-versus-host disease (GVHD) severity levels and overall survival rates may be advantageous for allogeneic hematopoietic cell transplant patients; nevertheless, a number of issues still need to be resolved. Furthermore, more recent drug approvals for the prevention and treatment of chronic (GVHD) include Jakafi and Rezurock, which may be more beneficial than earlier ones.
Key Segments Profiled in Market:
By Product:
- Monoclonal antibodies
- mTOR inhibitors
- Tyrosine kinase inhibitors
- Thalidomide
- Etanercept
By Disease:
- Acute Graft Versus Host Disease (aGvHD)
- Chronic Graft Versus Host Disease (cGvHD)
By Region:
- North America
- Latin America
- Europe
- Asia Pacific
- Middle East & Africa
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