The global graft versus host disease treatment market is on a strong growth trajectory, with an estimated valuation of USD 2,713.6 million in 2023. According to recent projections, the market is expected to expand at a robust Compound Annual Growth Rate (CAGR) of 8.2%, reaching approximately USD 5,960.7 million by 2033.
GvHD, a serious complication that can occur after hematopoietic cell transplantation (HCT), is increasingly being managed with advanced treatment strategies. The market growth is driven by the rising adoption of corticosteroids and combination therapies, which have proven effective in treating GvHD and improving patient outcomes.
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Orencia (abatacept) was approved by the US Food and Drug Administration in December 2021 for the treatment of GVHD in both adult and pediatric patients. Orencia is used both to prevent and cure autoimmune disorders. This medication avoids the attack of T-cells, which are crucial in acute GVHD, by selectively attaching to and altering one of the major costimulation signals sent by these cells.
As a result, acute (GVHD) is avoided since T-cells are kept from fully activating. Surgeons are assessing a number of novel strategies to stop GVHD in the future.
Key Takeaways:
- The global graft versus host disease (GvHD) treatment market is expected to reach US$5.96 billion by 2033, growing at a CAGR of 8.2%.
- Rising adoption of combination therapies and advancements in allogeneic hematopoietic cell transplant (HCT) are key growth drivers.
- Newer medications like Jakafi and Rezurock offer improved efficacy for chronic GvHD compared to traditional treatments.
Recent improvements in acute graft-versus-host disease (GVHD) severity levels and overall survival rates may be advantageous for allogeneic hematopoietic cell transplant patients; nevertheless, a number of issues still need to be resolved. Furthermore, more recent drug approvals for the prevention and treatment of chronic (GVHD) include Jakafi and Rezurock, which may be more beneficial than earlier ones.
Key Segments Profiled in Market:
By Product:
- Monoclonal antibodies
- mTOR inhibitors
- Tyrosine kinase inhibitors
- Thalidomide
- Etanercept
By Disease:
- Acute Graft Versus Host Disease (aGvHD)
- Chronic Graft Versus Host Disease (cGvHD)
By Region:
- North America
- Latin America
- Europe
- Asia Pacific
- Middle East & Africa
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