The global downstream processing market, valued at USD 22.0 billion in 2021, is projected to experience significant expansion in the coming years. Driven by rising adoption among biopharmaceutical companies and contract research organizations (CROs), the market is forecasted to grow at a remarkable CAGR of 11.3% from 2022 to 2032. This growth trajectory will propel the market’s valuation to USD 24.9 billion by the close of 2022 and further to an impressive USD 72.3 billion by 2032.
A key factor fueling the downstream processing market’s growth is the increasing demand for biopharmaceuticals, which require highly efficient separation and purification processes. As biopharma companies and CROs continue to invest in these critical technologies, downstream processing tools are becoming indispensable across the industry.
Within the product segment, chromatography columns and resins emerged as dominant players in 2021, capturing approximately 37.9% of the market share. This segment is expected to maintain its lead through 2032 due to its essential role in purifying biomolecules and enhancing yield in biomanufacturing processes.
Key Market Insights
- Market Growth: The downstream processing market is driven by the rising adoption of biopharmaceuticals and contract research organizations (CROs), which are increasingly utilizing downstream processing techniques for drug development and manufacturing.
- Product Segmentation: The chromatography columns and resins segment held a substantial share of 37.9% in the global downstream processing market in 2021 and is expected to maintain its dominance throughout the forecast period (2022-2032). This segment’s growth is attributed to its critical role in purification processes essential for biopharmaceutical production.
- Technological Advancements: Innovations in chromatography techniques are enhancing the efficiency and effectiveness of downstream processing, enabling better separation and purification of biopharmaceutical products.
Market Dynamics
- Increasing Demand from Biopharmaceutical Sector: The biopharmaceutical industry is a significant contributor to market growth, driven by the need for advanced therapies and biologics, including monoclonal antibodies and vaccines. This sector’s expansion is creating a robust demand for effective downstream processing solutions.
- Contract Research Organizations (CROs): The growing reliance on CROs for drug development services is further propelling the demand for downstream processing products. CROs require efficient purification methods to ensure high-quality outputs in their research activities.
Regional Insights
- The North American region is anticipated to dominate the downstream processing market due to its established pharmaceutical industry and significant investments in biotechnological research and development.
- Emerging markets in Asia-Pacific and Latin America are also expected to witness substantial growth, driven by increasing healthcare expenditures and expanding biopharmaceutical sectors.
Competitive Landscape
Leading players in the downstream processing market are focusing on the development and launch of next-generation downstream processing products. Apart from that, they are concentrating on the expansion of their manufacturing capabilities with high flexibility and rapid operations.
A few of these strategies undertaken by the market players in the downstream processing market are:
- In April 2022, Thermo Fisher Scientific opened a bioprocessing manufacturing site in Ogden, Utah, for the development of biologics and vaccines.
- In May 2022, Sartorius began focusing on the growth of its global production capacity with the expansion of its manufacturing site in Tunisia.
- In June 2022, Bio-Rad introduced the CHT™ prepacked Foresight Pro Columns in order to serve downstream process-scale chromatography applications throughout all stages of biological drug research and manufacture.
Key Companies Profiled
- Thermo Fisher Scientific Inc.
- GE Healthcare
- Sartorius Stedim Biotech S.A.
- Merck Millipore
- Danaher Corporation
- 3M Company
- Boehringer Ingelheim
- Lonza Group AG
- Eppendorf AG
- Finesse Solutions, Inc.
- Bio-Rad Laboratories
- Agilent technologies
- Solida Biotech GmBH
- Waters Corporation
- Applikon BioTechnique/Getinge AB
A Full Report Overview
Key Market Segments Covered In the Downstream Processing Industry Research
By Product:
- Chromatography Columns and Resins
- Membrane Adsorbers
- Single-use Products
- Consumables and Accessories
By Technique:
- Separation
- Concentration
- Purification
By Application:
- Monoclonal Antibody Production
- Vaccine Production
- Insulin Production
- Immunoglobulin Production
- Erythropoietin Production
- Other Application
By End User:
- Biopharmaceutical Companies
- CDMO/Contract Research Organization
- Research/Academic Institutes
By Region:
- North America
- Latin America
- Europe
- South Asia
- East Asia
- Oceania
- Middle East and Africa (MEA)
Author By:
Sabyasachi Ghosh (Associate Vice President at Future Market Insights, Inc.) holds over 12 years of experience in the Healthcare, Medical Devices, and Pharmaceutical industries. His curious and analytical nature helped him shape his career as a researcher.
Identifying key challenges faced by clients and devising robust, hypothesis-based solutions to empower them with strategic decision-making capabilities come naturally to him. His primary expertise lies in areas such as Market Entry and Expansion Strategy, Feasibility Studies, Competitive Intelligence, and Strategic Transformation.
Holding a degree in Microbiology, Sabyasachi has authored numerous publications and has been cited in journals, including The Journal of mHealth, ITN Online, and Spinal Surgery News.
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