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Organ on a Chip Kit: Market Insights

Organ on chip is a recently developed multidisciplinary field in which human cell biology and microfluidics are combined on top of lab on chip architecture. Organ on a chip is one of the fastest growing application in the research areas in life science and pharmaceuticals industries. Organ on a chip is multi-channel microfluidic cell which stimulates the physiological response, activities and response of the organ and organ system, type of artificial organ. Increasing in adoption organ on a chip will abolish the need for animals in toxin testing and drug development. Organ on a chip are used especially for research activity in the advanced biomedical engineering field such as bioMEMS, micro fabrication and microelectronics. Organ on chip creates new and innovative ways to culture cells and tissues which offer precise and continuous control during complete culturing process. Organ on a chip have significant impact on the improvement on the predictability of drug screening models and personalized medicines. Multiple organs can be placed on the chip and re interconnected to model the dynamics of human organism which is possible due to 3D cell culture, micro fluids and 3D printing technologies which allow the cultivation of cells from patients which reflects phenotype or genotype. Different companies and universities are continuously looking for better and new models in the development of drugs with collaboration with different manufacturing companies. In the long term, the organ on a chip technology helps in the advanced human based and personalized research and development of drugs.

Organ on a chip kit: Market Dynamics

Increase in innovation in drug development and growing prevalence of chronic disease such as respiratory disease, heart failure and other disease drive the market of organ on a chip kit market. Rising awareness among the population towards better healthcare devices propel the growth of organ on a chip kit market globally. Increase in healthcare expenditure and increase rate of organ transplant is expected to boost the demand of organ on a chip kit market during the forecast period. However, high cost associated with the kit of organ on chip and lack of adoption of innovative technology in the under developed economies hamper the growth of the organ on a chip kit market.

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Organ on a Chip Kit Market: Region-wise Outlook

On the basis of geography, global organ on a chip kit market is segmented into seven key regions viz. North America, Latin America, Western Europe, Eastern Europe, Asia Pacific excluding Japan, Japan, and Middle East & Africa. North America is projected to hold largest shares in the global Organ on a Chip Kit Market primarily due to growing adoption of innovative technologies to cure disease which are chronic. Increase in research and development activities and rise in healthcare applications in North America drive the market of organ on chip kit.  Europe is anticipated to be the second in the revenues share. Asia Pacific region is anticipated to be the fastest growing region in organ on chip kit market owing to increase in investment in the research and development in the drug development and government initiative towards the improvement of healthcare expenditure. Latin America and Middle East & Africa is expected to show slow growth due to lack of awareness among the population and high cost associated with organ on a chip kit market in near future.

Organ on a Chip Kit Market: Key Players

Some of the key players present in global organ on a chip kit market are Micronit Microtechnologies B.V, F. Hoffmann-La Roche Ltd, MIMETAS B.V., Nortis, CN Bio Innovations, TissUse GmbH, Koninklijke Philips N.V., and others

The research report presents a comprehensive assessment of the market and contains thoughtful insights, facts, historical data, and statistically supported and industry-validated market data. It also contains projections using a suitable set of assumptions and methodologies. The research report provides analysis and information according to market segments such as geographies, application, and industry.

The report covers exhaust analysis on:

• Market Segments
• Market Dynamics
• Market Size
• Supply & Demand
• Current Trends/Issues/Challenges
• Competition & Companies involved
• Technology
• Value Chain

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Regional analysis includes:

• North America (U.S., Canada)
• Latin America (Mexico. Brazil)
• Western Europe (Germany, Italy, France, U.K, Spain)
• Eastern Europe (Poland, Russia)
• Asia Pacific (China, India, ASEAN, Australia & New Zealand)
• Japan
• Middle East and Africa (GCC Countries, S. Africa, Northern Africa)

The report is a compilation of first-hand information, qualitative and quantitative assessment by industry analysts, inputs from industry experts and industry participants across the value chain. The report provides in-depth analysis of parent market trends, macro-economic indicators and governing factors along with market attractiveness as per segments. The report also maps the qualitative impact of various market factors on market segments and geographies.

The global organ on a chip kit market is segmented by drug type and distribution channel:

Examples of some of the key players in the coagulation disorders market are Bio-Rad Laboratories, Hoffman-La Roche Ltd., Griflos S.A., Abbott, Becton Dickinson, B Braun, Fresenius Kabi, Haemonetics Corporation, Immucor, Kidde-Fenwal and Macopharma,Quotient Limited, NOW Foods, Pure Micronutrients, Bayer AG, Nature’s Bounty Co., Sundown Naturals, Shaklee Corporation, MegaFood, Solgar Inc., Helena Laboratories, VitroScient, Guangzhou Wondfo Biotech, AB ANALITICA s.r.l. and Randox Laboratories

Coagulation disorder is a condition that affects the way blood normally clots. This clotting process is generally known as coagulation. For the blood to clot, the body requires certain proteins called clotting factors and blood cells called platelets. Normally, at the site of injured or damaged blood vessels, the clotting factors come together and form a fibrin clot. The clot helps in keeping the platelets in place and prevents the blood from flowing out. In people with coagulation disorders, the platelets or clotting factors don’t work the way they should or there’s a deficiency of clotting factors or platelets. When the blood doesn’t coagulate, it can lead to excessive or prolonged bleeding. Absence of the required number of platelets and clotting factors can also lead to sudden bleeding in the joints, muscles or other parts of the body. Majority of the coagulation disorders are inherited. However, some of the coagulation disorders may develop as a result of other medical conditions such as liver disease. Some of the common types of coagulation disorders are hemophilia A, hemophilia B, and Von Willebrand’s disease. The diagnosis requires various blood tests to be conducted such as Complete Blood Count (CBC) test and bleeding time test. The treatment of coagulation disorders vary depending on the type of bleeding and its severity. Though the treatment cannot cure coagulation disorders, they can help relieve the symptoms associated with it.

Factors Driving and Restraining the Coagulation Disorders Market

Government initiatives and an increase in healthcare expenditure have improved the quality of healthcare services. This has increase the demand for coagulation disorder test kits and treatments. Increase in the geriatric population will further drive the growth of coagulation disorders market. Increase in population has spurred the demand for diagnostic tests and treatments, this has spurred the growth of coagulation disorders market. However, high costs and risks associated with treatment and tests may have a negative impact on the coagulation disorders market. With technological advances these risks can be minimized. Stringent government regulations may also restrain the growth of coagulation disorders market.

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Regional Outlook

The global market for coagulation disorders is segmented into North America, Latin America, Europe, Asia Pacific, Japan, and Middle East & Africa. North America leads the coagulation disorders market. Increasing number of coagulation disorder cases and high adoption rate for various tests and treatment are attributed to North America’s high market share. Northern Europe is the second large market for coagulation disorders. A steady rise in the demand for test kits and treatments have accelerated the growth of coagulation disorders in Eastern Europe. A surge in the number of coagulation disorder cases and increase in demand for various treatments fuel the growth of coagulation disorders market in Asia Pacific.

Research Methodology

FMI utilizes a triangulation methodology that is primarily based on overall expenditure on life science research and R&D funding and capital equipment installed base to obtain precise market estimations and insights on life science and biotechnology associated products, technologies, applications and services. Bottom-up approach is always used to obtain insightful data for the specific country/regions. The country-specific data is again analysed to derive data at a global level. This methodology ensures high quality and accuracy of information.

Secondary research is used at the initial phase to identify the feasibility of the target products/technology categories and its respective segments, product and service offerings, equipment installed base in end use facilities, adoption rate and future impact of new technologies. Additionally, per capita consumption of kits, reagents and consumables among end users is tracked at a granular level to obtain the most accurate information. Each piece of information is eventually analysed during the entire research project which builds a strong base for the primary research information.

Primary research participants include demand-side respondents such as laboratory managers, procurement managers, research supervisors at academic and research institutes, as well as key opinion leaders in addition to supply-side respondents such as equipment and reagent manufacturers, custom solution and service providers who provide valuable insights on trends, research application of products and technologies, purchasing patterns, services offered and associated pricing.

Quantitative and qualitative assessment of basic factors driving demand, economic factors/cycles and growth rates and strategies utilized by key players in the market is analysed in detail while forecasting, in order to project year-on-year growth rates. These Y-o-Y growth projections are checked and aligned as per associated industry/product lifecycles and further utilized to develop market numbers at a holistic level.

On the other hand, we also analyse annual reports of various companies, investor presentations, SEC filings, 10k reports and earning call transcripts operating in the market to fetch substantial information about the market size, trends, opportunity, drivers, restraints and to analyse key players and their market shares. Key companies are segmented at tier-level based on their revenues, product portfolio and presence.

Please note that these are the partial steps that are being followed while developing the market size. Besides this, forecasting will be done based on our internal proprietary model which also uses different macro-economic factors such as overall life science research expenditure, R&D funding, industry based demand driving factors impacting the market and its forecast trends apart from other macroeconomic factors.

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Key Data Points Covered in Report:-

• Coagulation Disorders Market by Type, Test, End users and Region
• Regional level market analysis of North America, Latin America, Western Europe, Eastern Europe, Asia Pacific Excluding Japan, Japan, Middle East & Africa by test type, end use segments and country
• Coagulation Disorders Market Dynamics & Opportunity Assessment
• Historical Actual Market Size of Coagulation Disorders analysis, 2013 – 2017
• Coagulation Disorders Market Size & Forecast 2018-2028
• Competition & Companies involved.

Conventionally, pharmaceutical thermal analysis was mainly employed in research and development, but it has gained substantial influence in the pharmaceutical industry over the years. Commercially, advancements in techniques and applications have become extremely important to the pharmaceutical industry as they increase the sensitivity and decrease the time taken considerably. The dramatic decrease in the time taken will account for enormous economic benefits. Pharmaceutical thermal analysis tools can be found in nearly all analytical development and formulation laboratories within the pharmaceutical industry.

Recent Developments in Pharmaceutical Thermal Analysis Market

Initially, there were primarily two differential scanning calorimetry instruments – Power Consumption Differential Scanning Calorimetry and Heat Flux Differential Scanning Calorimetry Analyzer. However, recent advancements in techniques of differential calorimetry analysis have given rise to two more versions – Modulated DCS and Tzero DCS – with significant improvements in resolution and sensitivity. These advanced technologies result in accurate characterization of a wide range of crystalline and amorphous pharmaceutical materials including proteins, tablets and frozen solutions.

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Factors Driving the Pharmaceutical Thermal Analysis Market

The global market for pharmaceutical thermal analysis market is driven by analytical developments within the industry, which illustrates the importance of analytical methodologies. Pharmaceutical thermal analysis offers versatile tools for the successful analysis and development of pharmaceutical products. It also plays a substantial role in research and development, enabling research organizations to explore the properties of various materials.

Regional Outlook

Geographically, the pharmaceutical thermal analysis market can be segmented into North America, Latin America, Europe, Asia Pacific, Japan and Middle East & Africa. North America accounts for the largest share of the pharmaceutical thermal analysis market, which can be attributed to the increasing industrial R&D expenditure and the availability of public and private funding for research studies. Europe is pegged to be next in line with a substantial market share, followed by Asia Pacific.

Competition Outlook

Some of the key players in the pharmaceutical thermal analysis market are Waters (US), NETZSCH (Germany), LINSEIS (Germany), Mettler-Toledo (US), PerkinElmer (US), SETARAM (France), and Shimadzu (Japan), Particle Technology Labs Ltd, RJ Lee Group Inc., Harper International Corporation, Westmoreland Mechanical Testing & Research Inc., Particle Technology Labs Ltd, RJ Lee Group Inc., TE Connectivity India Sales Office, Anderson Materials Evaluation Incorporated, Harper International Corporation and Westmoreland Mechanical Testing & Research Inc.

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Research Methodology

FMI utilizes a triangulation methodology that is primarily based on the overall expenditure on life science research and R&D funding and capital equipment installed base to obtain precise market estimations and insights on life science and biotechnology associated products, technologies, applications and services. The bottom-up approach is always used to obtain insightful data for the specific country/regions. The country-specific data is again analysed to derive data at a global level. This methodology ensures high quality and accuracy of information.

Secondary research is used at the initial phase to identify the feasibility of the target products/technology categories and its respective segments, product and service offerings, equipment installed base in end use facilities, adoption rate and future impact of new technologies. Additionally, per capita consumption of kits, reagents and consumables among end users is tracked at a granular level to obtain the most accurate information. Each piece of information is eventually analysed during the entire research project which builds a strong base for the primary research information.

Primary research participants include demand-side respondents such as laboratory managers, procurement managers, research supervisors at academic and research institutes, as well as key opinion leaders in addition to supply-side respondents such as equipment and reagent manufacturers, custom solution and service providers who provide valuable insights on trends, research application of products and technologies, purchasing patterns, services offered and associated pricing.

Quantitative and qualitative assessment of basic factors driving demand, economic factors/cycles and growth rates and strategies utilized by key players in the market is analysed in detail while forecasting, in order to project year-on-year growth rates. These Y-o-Y growth projections are checked and aligned as per associated industry/product lifecycles and further utilized to develop market numbers at a holistic level.

On the other hand, we also analyse the annual reports of various companies, investor presentations, SEC filings, 10k reports and earning call transcripts operating in the market to fetch substantial information about the market size, trends, opportunity, drivers, restraints and to analyse key players and their market shares. Key companies are segmented at tier-level based on their revenues, product portfolio and presence.

Please note that these are the partial steps that are being followed while developing the market size. Besides this, forecasting will be done based on our internal proprietary model which also uses different macro-economic factors such as overall life science research expenditure, R&D funding, industry based demand driving factors impacting the market and its forecast trends apart from other macroeconomic factors.

Key Data Points Covered in Report:

• Pharmaceutical thermal analysis market by technique, application, end users and region
• Regional level market analysis of North America, Latin America, Western Europe, Eastern Europe, Asia Pacific Excluding Japan, Japan, Middle East & Africa by test type, end use segments and country
• Pharmaceutical thermal analysis market dynamics & opportunity assessment
• Historical actual market size of pharmaceutical thermal analysis, 2013 – 2017
• Pharmaceutical thermal analysis market size & forecast, 2018 – 2028
• Competition & companies involved

The pharmaceutical thermal analysis market can be segmented on the basis of the following parameters:

However, the high price of pharmaceutical dosage form testing systems may act as a restraint for the global pharmaceutical dosage form testing systems market over the forecast period. Additionally, the dearth of skilled personnel for operating pharmaceutical dosage form testing systems is also creating a hurdle for the growth of the said market.

Pharmaceutical dosage form testing systems are used to verify the efficacy and bioavailability of a drug formulation. The evaluation and assessment of a tablet’s chemical, physical, and bioavailability properties are especially important in tablet design and for monitoring product quality. Various standards should be used to control the pharmaceutical quality of tablet dosage forms. The standard QC tests carried out on tablets include weight variation, content uniformity, diameter and thickness, hardness, friability, disintegration, and dissolution. It is imperative to test for formulary stability and potential drug degradation. Dosage form testing also verifies the physical strength of formulation. Pharmaceutical dosage form testing systems have additional features such as vibration-free tablet separation, auto separation and auto alignment.

Numerous tests are performed at every stage of production to ensure that quality is not compromised and that Good Manufacturing Practices are followed. Quality checks are crucial to the pharmaceutical industry as they guarantee the patient a safe and effective product and further, protect the manufacturer against compensation claims.

Pharmaceutical dosage form testing systems ensure that a quality end product reaches the end consumer, which is a key factor anticipated to propel the demand for pharmaceutical dosage form testing systems worldwide.

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Regional Outlook

On the basis of regional presence, the global pharmaceutical dosage form testing systems market can be segmented into eight key regions: North America, Latin America, Western Europe, Eastern Europe, Asia-Pacific excluding China and Japan (APCEJ), China, Japan and Middle East & Africa. North America is pegged to dominate the global pharmaceutical dosage form testing systems market with a leading share in terms of revenue. The market in the region is expected to register significant growth over the forecast period, owing to technological advancements and the presence of developed medical infrastructure. Europe, followed by North America, is slated to hold a moderate share and register a healthy growth rate in the global pharmaceutical dosage form testing systems market.

APECJ and China are emerging as lucrative markets for pharmaceutical dosage form testing systems and are anticipated to register significant shares over the forecast period due to the increasing demand for these systems and developing medical infrastructure in the regions. Latin America and MEA are at a nascent stage in the global pharmaceutical dosage form testing systems market and are expected to exhibit moderate growth over the forecast period, owing to the increasing medical facilities in these regions.

Market Participants:

Some of the market players in the global pharmaceutical dosage form testing systems market include SOTAX AG, ABC Laboratories, Almac, Dalton Pharma Services, GEA Process Engineering, Micromeritics Instrument Corporation, Quality Chemical Laboratories and SCYNEXIS, Inc.

The report covers exhaustive analysis on:

• Pharmaceutical dosage form testing systems market segments
• Pharmaceutical dosage form testing systems market dynamics
• Historical actual market size, 2013 – 2017
• Pharmaceutical dosage form testing systems market size & forecast 2018 to 2028
• Pharmaceutical dosage form testing systems market current trends/issues/challenges
• Competition & companies involved
• Pharmaceutical dosage form testing systems market drivers and restraints

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Regional analysis includes

• North America
• Latin America
• Western Europe
• Eastern Europe
• Asia Pacific excluding China and Japan (APECJ)
• China
• Japan
• Middle East & Africa

The global pharmaceutical dosage form testing systems market can be segmented on the basis of device type, dosage type, test type and end user.