Treatment for cervical cancer- characterized by uncontrolled growth of cells in the cervix, will witness a significant demand in the coming years, considering early diagnosis of cervical cancer arising from increased awareness among women. As per the American Cancer Society, nearly 13,240 new cases of invasive cervical cancer will be diagnosed in US, by the end of 2018 and nearly 4,170 women would succumb to cervical cancer.
Increased Use of HPV, Pap-Test to Drive Cervical Cancer Treatment Landscape, Specifically in Low-Resource Economies
As per world cancer statistics, nearly 80 percent of cervical cancer cases are found in women in low-resource and developing nations. Apart from lack of awareness, difficulties in conducting cytology-based screening programs also play a major role in delaying cervical cancer treatment, in such economies including India. Medical experts emphasize on having a robust pre-screening protocol, which is essential in detecting early cervical epithelial changes. Pap-Smear test remains the single largest screening test for detecting early stage of invasive cervical cancer and precancerous cervical intraepithelial neoplasia. In the United States, Center for Disease Control and Prevention (CDC)-sponsored National Breast and Cervical Cancer Early Detection Program (NBCCEDP) helps women get timely screening – both uninsured and insured low-income women. Studies indicate nearly 60 percent reduction in cervical cancer death, after the implementation of Pap-Smear Test.
However, in Australia, on the other hand, the government-funded initiative National Cervical Screening Program (NCSP) is aimed at reducing cervical cancer cases in the region. In December 2017, under this program, the pap test was replaced with a Cervical Screening Test that looked at the human papillomavirus (HPV) – cause of nearly cervical cancer in 99 percent cases. Several studies also indicate HPV tests being more accurate than pap-smear for cervical cancer screening. Moreover, the American Society of Clinical Oncology, called for quantifiable trials of HPV testing to test the efficacy of HPV tests over pap-smear.
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Immunotherapy, Targeted Therapies Could Soon Become Frontline Cervical Cancer Treatment Choices
Although cervical cancer treatment has undergone significant refinement in the last two decade, patients with FIGO stage IIB-IVA (locally advanced disease) often fail to achieve complete response to CCRT (concurrent chemo-radiation) – with either Cisplatin or in combination. Research and medical experts are developing advanced approaches to improve outcomes of cervical cancer treatment. For instance, an inhibitor of vascular endothelial growth – bevacizumab (mostly sold under the trade name Avastin)—is said to showcase improved result in recurrent or metastatic cervical cancer cases when used along with chemotherapy. Researchers are also exploring the prospects of adjuvant chemotherapy given to patients with stage III-IVA disease and positive lymph nodes and tumor volume, after CCRT. Apart from combination therapies, cervical cancer treatment options involving targeting molecular pathways with innovative agents, are also being studies.
In addition, immune-based therapies, has been touted as the most promising alternative to prevent, treat, and cure cancer. Oncologists and medical experts are anticipated to study the effectiveness of immunotherapy, for cervical cancer treatment, including checkpoint inhibitors-for blocking cancer cells’ ability to harm the immune system and treatment vaccines- for inducing a response against the cancer cells. For instance, Axalimogene filolisbac, already studies in six clinical trials, is being touted as the most unique immunotherapy for HPV-related cancers.
Clinical Trials, Research and Development Gains Prominence among Key Manufacturing Companies
Institut Curie, recently launched a new clinical trial, under the name of NiCOL, with a focus on patients suffering from late-stage cervical cancers. Aimed at assessing the optimal dosage of Nivolumab, monoclonal antibodies, researchers are said to assess the clinical effectiveness of NiCOL, along with its immunological and genetic mechanisms during the pelvic chemo-radiotherapy stage.
Iovance Biotherapeutics, Inc, on the other hand, are studying the efficacy of LN-145, an autologous tumor-infiltrating lymphocyte (TIL), aimed at providing a second-line option for cervical cancer treatment- recurrent metastatic, and persistent. In a sponsored study by National Institutes of Health (NIH), TIL therapy showed thorough regression of metastatic cervical cancer.
Under more such developments, the US Food and Drug Administration (FDA), granted its approval to Keytruda, developed by Merck, after its got priority review for cervical cancer treatment, in March 2018.
The in-depth analysis of the cervical cancer treatment market offers a detailed evaluation on the basis of historical, current, and forecast data facts. The report on cervical cancer treatment offers qualitative and quantitative insights-using adequate primary and secondary research methodologies. The research report on cervical cancer treatment market, apart from the segmental analysis, offers a detailed analysis on:
- Cervical cancer treatment market key Segment
- Cervical cancer treatment Market Influencers
- Cervical cancer treatment Market Market Size
- Cervical cancer treatment Market Key Trends and Opportunities
- Cervical cancer treatment Market Supply and Demand Analysis
- Cervical cancer treatment Market Value Chain and Pricing Analysis
- Cervical cancer treatment Market Key Market Participants
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Geographical Assessment of Cervical cancer treatment Market includes:
- North America Market of Cervical cancer treatment Market including Canada and US.
- Latin America Cervical cancer treatment Market including Mexico, Brazil, and Rest of Latin America.
- Western Europe Cervical cancer treatment Market including Germany, Italy, U.K, France, Nordic countries, Netherlands, Spain, Luxembourg, Belgium, and Rest of Western Europe.
- Eastern Europe Cervical cancer treatment Market including Poland, Russia, and Rest of Eastern Europe.
- Asia Pacific Cervical cancer treatment Market including China, India, ASEAN, Australia & New Zealand.
- Japan Truck Cervical cancer treatment Market
- Middle East and Africa Cervical cancer treatment Market including GCC, South Africa, and Rest of MEA.
The cervical cancer treatment Market research study is an outlook of first-hand information gained by analyzing the market in a qualitatively and quantitatively. This data is gained with the help of research analysts, experts in the industry and participants across the value chain. The thorough assessment of the trends in the parent market, macro-economic metrics, market governing factors, and market attractiveness based on segments are all included in the report. The Cervical cancer treatment Market study also traces the influence of the several factors on the regions and market segments.
Cervical Cancer Treatment Market
The report of cervical cancer treatment market, offers an in-depth segmental analysis:
On the basis of disease indication, the cervical cancer treatment market is divided into
- Pre-malignant lesions- Cervical Intraepithelial Neoplasia (CIN-1, CIN-2, CIN-3)
- Early invasive stage (IA – IB1 – IIA1)
- Advanced invasive stage (IB2 – IIA2 – IIB – IIIA – IIIB – IVA)
On the basis of treatment type, the cervical cancer treatment market is divided into
- Chemotherapy (cisplatin, carboplatin, paclitaxel, doxorubicin, gemcitabine, bevacizumab etc).
- Cryotherapy.
- Targeted therapy (bevacizumab, Pazopanib).
- Hormone therapy (oestrogen, progesterone, progestogens and testosterone).
- Simple hysterectomy.
- Radiation therapy (Brachytherapy-BT and External beam therapy-EBT).
- LEEP- Loop electrosurgical excision procedure
- Cold knife conization.
- Laser surgery.
- Cone biopsy.
- Radical trachelectomy.
- Radiation therapy (Brachytherapy-BT and External beam therapy-EBT).
On the basis of end user, the cervical cancer treatment market is divided into
- Hospitals.
- Diagnostic centers.
- Cancer Palliative care clinics.
- Pharmacies.
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Report Highlights:
- Detailed overview of Parent Market
- Changing Dynamics of Cervical cancer treatment Market
- Thorough Market Classification
- Cervical cancer treatment Market Size with respect to Volume and Value: Current, Historical and Projected Data
- Latest industrial trends and developments
- Cervical cancer treatment Market -Competitive Landscape
- Major Players in Cervical cancer treatment Market – Strategies and Product offerings
- Geographies and Potential and Niche Segments that exhibit promising growth
- Neutral perspective of Cervical cancer treatment Market Performance
- Necessary information for Companies to help improve and sustain their presence in the market