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Those who undergo hemodialysis on regular basis are at the highest risk of contracting HA-MRSA. Further, those staying in nursing homes and the ones who had been hospitalized are also at risk.
On the other hand, CA-MRSA prevalence is higher among individuals involved in contact sports, the ones living in unhygienic conditions, and those working in day care centers.
Oral antibiotics are administered to MRSA-infected patients as the first course of action. Vancomycin is one such antibiotic recommended by IDSA (Infectious Disease Society of America).
With increasing incidences of MRSA across the globe (with the U.S., Canada, Japan, and Indonesia having the highest rates as per the WHO), the demand for the above-mentioned oral antibiotic is likely to increase manifold, thereby boosting the MRSA treatment market.
Covid-19 Crisis Impact – Significant Rise in Secondary MRSA Infections to Catalyze the Market
The outbreak of Covid-19 has increased the risk of secondary infections. Covid-19 positive individuals are reported to be more vulnerable to MRSA infections.
According to Centers for Disease Control (CDC) 1 in 7 Covid-19 hospitalized patients have contracted secondary bacterial infections, and the infection has proven to be fatal in 50% of these patients.
These factors are likely to raise short-term demand for first-line antibiotic treatment against secondary MRSA infections in Covid-19 patients.
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MRSA Treatment Market Moderately Consolidated with a Few Specialized Industry Players
The key players are on the “innovation” spree to consolidate their market share. Everyone – right from top tier innovator companies to small size developer companies are looking out for differentiators in this regard. The top-notch players are going for production of new antibiotics, acquisition, and exclusive product licensing to mitigate the entry of small and new companies. The other strategies followed are “exclusive distribution” and “development collaborations”.
Although advanced MRSA treatments have sprung up all over the globe, most of the leading manufacturers are U.S.-based.
Pfizer Inc. alone owns a significant share of the U.S. market, but the marketplace is rapidly becoming competitive owing to gains made by players such as Melinta Therapeutics, Inc. The company received FDA approval for Baxdela (delafloxacin) for extended indication in the treatment of acute bacterial skin and skin structure infections (ABSSSI) caused by susceptible bacteria).
In January 2018, Cutis Pharma Inc., a US based specialty pharmaceutical company, obtained approval for its Firvanq (vancomycin hydrochloride) oral solution for gastrointestinal infection of MRSA.
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MRSA Treatment: Region-wise Analysis
North America continues to be the most lucrative market for MRSA treatment. The US MRSA treatment market has grown steadily over the last five years, and is set to grow at over 3.8% in 2020.
University of Melbourne’s researchers state that “Teixobactin” responds positively against MRSA. This will surge the MRSA treatment market all over Australia and the other countries in Asia-Pacific.
Besides, Asia-Pacific is amongst the regions having the highest number of MRSA-infected population. Multilocus Sequence type (ST) 239 and ST5 – two pandemic HA-MRSA clones have spread across the region.
CA-MRSA’s molecular epidemiology gets identified by “clonal heterogeneity”; analogous to Europe. Another area to look into is “MRSA strains in livestock” in both these regions. Studies are being conducted to mitigate infections from livestock.
Competitive Landscape
The MRSA treatment market is witnessing the entry of new players, albeit at a local or regional level. With an estimated 20+ MRSA treatment players, clinical developments, new product launches, have become key avenues for being a class apart.
As of now, the players are concentrating on dosage in topical form. As such, clinical trials are being conducted to devise unique drug molecules. Besides, “research and development” is of prime focus over here. Just like the Brazilian peppertree; research is “ON” regarding positive outcomes from the other plants.
Some of the key players in the MRSA treatment market are:
Americas
- Pfizer, Inc.
- Allergan Plc.
- Johnsons & Johnson
- Merck & Co., Inc.
- Baxter Healthcare Corporation
- Bausch Health Companies Inc.
- Cumberland Pharmaceuticals Inc.
- Mylan N.V.
- Melinta Therapeutics, Inc.
- Akron Pharma Inc.
- Amneal Pharmaceuticals, Inc.
- Herbal Intervention, LLC
- Bio-Germ Protection LLC
Europe
- Novartis AG
- Debiopharm International SA
- Fresenius Kabi LLC
Asia Pacific
- Teva Pharmaceutical Industries Ltd.
- Sun Pharmaceutical Industries Ltd.
- Dr. Reddy’s Laboratories Ltd.
- Mayne Pharma Group Limited.