ESOMAR-certified Future Market Insights (FMI) has recently published an exhaustive yet unbiased analysis of the global Gaucher and Pompe disease ERT market providing insights on key growth trends through 2030.
As the global burden of genetic disorders such as Gaucher disease, Fabry disease, Pompe disease and other abnormalities rise, healthcare providers are scrambling to develop potential therapeutic approaches to offset their impacts.
According to the National Gaucher Foundation, one in every 450 people belonging to the Ashkenazi Jewish community suffer from Type-1 Gaucher disease, the most prevalent form, thereby opening up credible growth prospects for the future.
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Key Takeaways
- Gaucher and Pompe Disease ERT market to expand at 5.6% value CAGR through 2020
- Type-1 non-neuronopathic Gaucher disease to remain key treatment area, accounting for over 90% revenue by 2020-end
- Parenteral ERT administration to be most frequent, attributed to high demand for precision-based medicine
- Online pharmacies gaining credible impetus, expanding at over 7% CAGR through 2030
- Europe to retain lucrativeness, North America to be the 2nd largest market by 2030
COVID-19 Impact Analysis
As healthcare organization reorient their resources to fight the coronavirus pandemic, the market for Gaucher & Pompe Disease ERT experienced a substantial blip in the initial months, with treatment sessions declining significantly across several countries.
For instance, until July 2020, Spain recorded a 25% decline in enzyme replacement therapy sessions amongst people suffering from Type-1 and Type-3 Gaucher Disease respectively. This largely occurred as a consequence of rescheduling treatments at a later date.
In the United States, hospital visits to avail ERT have registered considerable decline for avoiding exposure to COVID-19 patients. As a result, patient self-administration at home have burgeoned. Furthermore, the pandemic has provided an opportunity to undertake research on lysosomal dysfunction and disease pathogenesis which would enhance clinical care.
Competitive Landscape
Prominent players operating in the Gaucher & Pompe Disease ERT landscape include Shire PLC, Ultragenyx Pharmaceuticals Inc., Sigma-Tau Pharmaceuticals Inc., Pfizer Inc., Alexion Pharmaceuticals Inc., Sanofi SA, Merck KGaA, Tadeka Pharmaceuticals, AbbVie Inc. and BioMarin Pharmaceutical Inc. to name a few.
Manufacturers rely on introduction of novel technologies to advance effective ERTs for numerous genetic conditions. For instance, in October 2018, the U.S Food & Drug Administration approved Sigma-Tau Pharmaceuticals’ (Lediant Biosciences) RevcoviTM injection for treating adenosine deaminase severe combined immune deficiency (ADA-SCID).
Likewise, Sanofi SA markets the Cerezyme® ERT injections through its Genzyme subsidiary, which offers a long term efficacy to elderly and pediatric patients suffering from Type-1 Gaucher Disease, and is the only known long-term cure for the condition.
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