The global sales of ibuprofen API, the main active ingredient in a well-known nonsteroidal anti-inflammatory drug, represent a sizeable portion of the pharmaceutical industry. The fact that ibuprofen API is used to make several analgesics and anti-inflammatory medications highlights the significance of this ingredient.The ibuprofen API market was estimated to be worth more than US$ 626.2 million in 2022 and is projected to grow at a compound annual growth rate (CAGR) of 3% to US$ 772.2 million by 2029, per the findings of a recent Future Market Insights (FMI) analysis. The size and age of manufacturing facilities, as well as the continued need for fairly priced non-steroidal anti-inflammatory drugs (NSAIDs), are the main factors propelling the growth of the Ibuprofen API market.
Increasing API drug shortages and assembling a task force to overcome these problems, the emergence of cost-effective drug manufacturers in various countries and the supply of API drugs, primarily in developing countries, are further driving ibuprofen API market growth.
The pharmaceutical API industry is witnessing a substantial crunch in supply and demand of Ibuprofen API, halted production from major ibuprofen API manufacturers, and supply chain disruption in China further led by declining sales in India.
The volatility in Ibuprofen API is due to factors such as a lower number of competitors, reduced utilization ratio, lower margin level, new higher-value opportunities in complex combinations and high-grade API, the pace of facility inspection by FDA, and ramping up production capacity of through mergers and consolidation.
The diverse range of diseases, primarily cardiovascular disease, infectious diseases, diabetes, and kidney-related complications, has a high prevalence, globally. Thus, the increasing prevalence of a diverse range of diseases among all age groups and its burden, globally, drives the demand for drug development and its market.
There has been an upsurge in the usage of advanced technologies, such as high throughput, bioinformatics and combinatorial chemistry for better drug candidate identification. Drug discovery has evolved significantly with emerging technologies, helping the process to become more refined, accurate, and less time-consuming. Due to automation, multi-detector readers, imaging hardware and software, high-throughput screening is one of the most widely used drug discovery technologies.
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Leading Companies Profiled in Ibuprofen API Market are
- BASF SE
- BIOCAUSE Inc.
- IOL Chemicals and Pharmaceuticals Limited
- SI Group, Inc.
- Sino-US Zibo Xinhua-Perrigo Pharmaceutical Co., Ltd.
- Solara Active Pharma Sciences Limited
- Granules India Limited
FMI Analyses the COVID-19 Impact on Market
FMI’s analysis suggests that the ongoing COVID-19 pandemic is having adverse impacts on market growth. Wuhan, China is the hub of API supplies. The region is the epicentre of the coronavirus outbreak, as such, it has temporarily halted its manufacturing facilities.
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Further, China is the prominent or the sole supplier of APIs including, penicillin and erythromycin, in the world. Manufacturers and distributors in the country are blaming logistical barriers and labour scarcity due to the COVID-19 pandemic for the delay in production and transportation.
Key Takeaways:
- Greater focus on relieving the pressure on the supply chain due to the demand gap is being tackled by ramping up production capacity, up-scaling is the fundamental strategy outlined for meeting demand in the Ibuprofen API space.
- Majority of the anti-inflammatory drugs are manufactured in Asia, especially in China and India. Approximately 80% of the total anti-inflammatory APIs are manufactured in India and China and most of the APIs manufactured in these countries are outsourced to other developed regions – North America and Europe.
- High upfront cost and lower margin level in Ibuprofen API have resulted in a 20-30% price spike in final drug formulations and lower sales in the previous year.
- The market for Ibuprofen API is consolidated in nature, with leading manufacturers holding around 90% of the market value as 90%. Hence, the growing interest of CMOs and large-scale API manufacturers is anticipated to boost the value creation of the ibuprofen API market.
- Higher volume handling by Contract Manufacturing Organizations in comparison to pharmaceutical companies and amid higher production capabilities and price advantage over pharmaceutical companies are expected to generate significant revenue pockets.
- Expanding patient pool consuming non-controlled drugs as OTC are also responsible for the growth of in-house ibuprofen API consumption in South and East Asia.
Lower labour cost and abundant availability of raw materials required for ibuprofen API are among the key factors fuelling the growth of the ibuprofen API market in South Asia. In addition, favourable regulatory support to establish ibuprofen API manufacturing businesses, and lower taxation policies are boosting the growth of the East and South Asia ibuprofen API market.
Capacity Expansion, and Strategic Mergers & Acquisitions to Widen Regional Presence
Leading players in the ibuprofen API market – SI Group, Inc., BASF SE, Hubei Biocause Pharmaceutical Co., Ltd. (BIOCAUSE Inc.), IOL Chemicals, Sino-US Zibo Xinhua-Perrigo Pharmaceutical Co., Ltd., and Solara Active Pharma Sciences Limited – are focusing on business expansions by mergers, joint ventures, distribution agreements and capturing the untapped potential of the Ibuprofen API market.
- In 2018, IOL Chemicals, the largest Indian Ibuprofen API manufacturer, expanded its production capacity to 12000 MT from the previous capacity of 7500 MT. With the increased capacity, IOL Chemicals is filling the demand-supply gap that is rising due to stringent regulatory reform in China. This move can further benefit the Indian manufacturers looking to strengthen their foothold in the Ibuprofen API market.
- The acquisition by Solara Active Pharma Sciences Limited in 2018 of the Ibuprofen API assets of Strides and Sequent enabled the company to capture the portfolio of niche segments of the Ibuprofen API market.
- The joint venture between Granules India Ltd (GIL) and Hubei Biocause Heilen Pharmaceutical Co. Ltd. have a production facility in Jingmen, China. In a recent discussion, Granules India Ltd (GIL) is planning to part out of the joint venture.
Additionally, current acquisitions are focused on capacity expansion, and manufacturing capabilities of existing Ibuprofen API players to gain competitiveness and accelerate revenue growth in the market landscape.
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Key Companies:
- BASF SE
- BIOCAUSE Inc.
- IOL Chemicals And Pharmaceuticals Limited
- SI Group, Inc.
- Sino-US Zibo Xinhua-Perrigo Pharmaceutical Co., Ltd.
- Solara Active Pharma Sciences Limited
- Granules India Limited
Key Segments:
Ibuprofen API Market by End User:
- Contract Manufacturing Organizations
- Pharmaceutical Companies
Ibuprofen API Market by Region:
- North America Ibuprofen API Market
- Latin America Ibuprofen API Market
- Europe Ibuprofen API Market
- East Asia Ibuprofen API Market
- South Asia & Pacific Ibuprofen API Market
- Middle East & Africa (MEA) Ibuprofen API Market
Author By:
Sabyasachi Ghosh (Associate Vice President at Future Market Insights, Inc.) holds over 12 years of experience in the Healthcare, Medical Devices, and Pharmaceutical industries. His curious and analytical nature helped him shape his career as a researcher.
Identifying key challenges faced by clients and devising robust, hypothesis-based solutions to empower them with strategic decision-making capabilities come naturally to him. His primary expertise lies in areas such as Market Entry and Expansion Strategy, Feasibility Studies, Competitive Intelligence, and Strategic Transformation.
Holding a degree in Microbiology, Sabyasachi has authored numerous publications and has been cited in journals, including The Journal of mHealth, ITN Online, and Spinal Surgery News.
About Future Market Insights (FMI)
Future Market Insights, Inc. (ESOMAR certified, recipient of the Stevie Award, and a member of the Greater New York Chamber of Commerce) offers profound insights into the driving factors that are boosting demand in the market. FMI stands as the leading global provider of market intelligence, advisory services, consulting, and events for the Packaging, Food and Beverage, Consumer Technology, Healthcare, Industrial, and Chemicals markets. With a vast team of over 5000 analysts worldwide, FMI provides global, regional, and local expertise on diverse domains and industry trends across more than 110 countries.
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