The global Alpha-1 Antitrypsin Deficiency (AATD) treatments market is anticipated to reach US$ 10 billion by 2033, growing at a compound annual growth rate of 12.8% from its projected US$ 3 billion market value in 2023. The increasing prevalence of respiratory ailments is one of the main factors propelling market expansion. In addition, the growing use of augmentation therapy is driving market growth.
The purpose of augmentation therapy is to increase the concentration of AAT in the respiratory tracts of patients by isolating the protein from healthy donors’ blood plasma. This treatment reduces the number of exacerbations, speeds up recovery, and decreases the emphysema’s growth. These components contribute to its increasing popularity among medical experts and patients.
It is also expected that research and development (R&D) investments will have a big impact on the sector. Many firms are working to create a portfolio that could alter the course of business by using their own competencies and expanding those through strategic alliances, R&D, and possible licensing, merger, and acquisition operations.
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Key Takeaways from the Market Study
- The global alpha-1 antitrypsin insufficiency market is expected to develop at a 12.8% CAGR by 2033, according to FMI.
- The global market for Alpha-1 Antitrypsin Deficiency is anticipated to be over US$ 3 billion.
- The global market for Alpha-1 Antitrypsin Deficiency is expected to be around US$ 10 billion.
- According to Future Market Insights, Asia Pacific will grow at a CAGR of 12% between 2023 and 2033.
- North America is expected to grow at a 12.7% CAGR between 2023 and 2033.
- Europe is expected to grow at a 12.3% CAGR between 2023 and 2033.
“Within North America, the United States has dominated the market. The rising number of government funding, developments in gene therapy research and development, and the rising penetration of target illnesses are the primary drivers driving the Alpha-1 Antitrypsin Deficiency market expansion,” says an analyst at FMI
Market Competition
To address the present patient pool’s requests and counter the therapeutic market’s unmet needs, drug developers are increasingly moving their focus to alpha-1 antitrypsin deficiency (AATD).
Many novel medicines are being developed by several businesses, including ARO-AAT (Arrowhead Pharmaceutical), Alvelestat (Mereo Biopharma), and Inhaled AAT (Kamada).
ARO-AAT (Arrowhead Pharmaceutical) is a second-generation subcutaneously given drug that lowers hepatic synthesis of the mutant AAT protein by knocking down the alpha-1 antitrypsin (AAT) gene transcript. The business is now undertaking Phase II clinical studies to assess the drug’s safety, tolerability, and pharmacodynamic impact in AATD patients.
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Key players in the Alpha-1 Antitrypsin Deficiency (A1ATD) market are:
- Pfizer
- Baxter
- AstraZeneca
- Grifols
- Teva Pharmaceutical Industries
- BoehringerIngelheim
- Kamada Ltd
- GlaxoSmithKline
- CSL Behring
- LFB Biomedicaments
Recent Developments:
Kamada Ltd., a vertically integrated global biopharmaceutical company focused on specialty plasma-derived therapeutics, announced in October 2022 that it had been awarded a three-year extension of an existing tender from the Canadian Blood Services (CBS) for the supply of four IgG products, CYTOGAM®, HEPAGAM®, VARIZIG®, and WINRHO® SDF, for a total estimated value of US$ 22 million. This award ensures that such products will continue to be sold in Canada. In November 2021, Kamada purchased four commercial pharmaceuticals that have been licensed by Health Canada and the United States Food and Drug Administration (FDA).
Key Segments Profiled in the Alpha-1 Antitrypsin Deficiency Market Industry Survey
By Product Type:
- Augmentation Therapy
- Bronchodilators
- Corticosteroids
- Oxygen Therapy
By Application:
- Hospitals
- Specialty Clinics
- Pharmacies
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